Pharmacological Treatment Of Diabetes Mellitus
This disease is subdivided into two categories type 1 and type 2.
Pharmacological treatment of diabetes mellitus. Evaluated interventions included metformin thiazolidinediones sulfonylureas dipeptidyl peptidase 4 dpp 4 inhibitors and sodium glucose cotransporter 2 sglt 2 inhibitors. Pharmacological treatment of diabetes mellitus is indicated when fasting glucose level exceeds 1600mg l. Diabetes can be managed pharmacologically using drugs such as insulin or oral hypoglycemic and non pharmacologically without drugs. Initiation titration of therapy.
Study quality was assessed data were extracted and results were. Diabetes mellitus is a disease characterized by the inability of peripheral tissues to uptake glucose caused by a deficit in insulin or insulin intolerance. In the united states 57 9 of patients with diabetes have 1 or more diabetes related complications and 14 3 have 3 or more. In recent years numerous pharmacological approaches for the treatment of type 2 diabetes mellitus t2dm have become available.
Non pharmacological treatment involves using exercises dietary and lifestyle modifications to control blood glucose. Comparative effectiveness of oral medications for type 2 diabetes. Abstract while lifestyle modifications and metformin are the cornerstone of the initial management of type 2 diabetes mellitus there is an increasing array of second and third line pharmacological agents for this condition. This article will focus on the non pharmacological treatment of diabetes.
The oral glucose lowering drugs are used for management of type ii. While all of them have proven blood glucose lowering effects identifying the most beneficial drug or drug combination for the treatment of an individual patient has become an increasing challenge. In patients diagnosed with diabetes mellitus dm the therapeutic focus is on preventing complications caused by hyperglycemia. Type 1 diabetes pertains to autoimmune destruction of pancreatic beta cells leading to the inability to produce sufficient amounts of insulin.