Lichen Sclerosis Histology
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Lichen sclerosis histology. Histology of lichen sclerosus. It usually affects the genital and anal areas. But it can also affect your upper arms torso and breasts. Vulvar lichen sclerosus ls a lymphocyte mediated chronic skin disease begins with uncharacteristic symptoms and progresses undiagnosed to atrophy and destructive scarring.
Lichen planus lp esp. Scanning power of lichen sclerosus reveals a lichenoid inflammatory pattern in early stage lesions or a superficial sclerosing process in late stage lesions figure 1 and 2. Usually flexor arms and legs glans penis and mucous membranes. Lp has wedge shaped hypergranulosis lacks.
Early ls is treatable although not curable. Morphea profunda deep fibrosis. The epidermis shows hyperkeratosis significant thinning with loss of the normal rete ridge pattern and plugging of follicular infundibulae figure 3. Differentiated vulvar intraepithelial neoplasia commonly co exists with lichen sclerosus.
Some patients with longstanding advanced ls have an increased risk of vulvar carcinoma. Lichen sclerosus is a rare skin condition that usually shows up on your genital or anal areas. Self limiting lasting 1 2 years although longer for oral lesions. May be confined to oral mucosa.
The condition mostly affects adult women. Lichen sclerosus ls is a chronic inflammatory skin disease of unknown cause commonly appearing as whitish patches on the genitals which can affect any body part of any person but has a strong preference for the genitals penis vulva and is also known as balanitis xerotica obliterans bxo when it affects the penis. Lp has wedge shaped hypergranulosis lacks basilar. Anyone can get lichen sclerosus but postmenopausal women are at higher risk.