Creatine Kinase Reference Range Uk
Ck is found predominantly in the heart muscle skeletal muscle and brain and are elevated when these muscle or nerve cells are injured.
Creatine kinase reference range uk. 32 294 u l. Other tissues such as kidney have low levels of enzyme activity. We are not a laboratory and are unable to comment on an individual s health and treatment. This article was last reviewed on.
They can rise within 6 hours after damage and if damage does not continue the levels peak at 18 hours after injury and return to normal in 2 to 3 days. Mft nhs uk laboratorymedicine 2 2 biological reference range or cut off. Ck is a type of protein known as an enzyme. 50 120 umol l urine male.
82 1 083 u l in men and 47 513 u l in women. A study of over 700 athletes suggests that normal reference ranges for athletes may be over two times higher than normal ranges. Reference ranges are dependent on. Creatine kinase ck is found in cardiac and skeletal muscle and brain.
Creatine kinase ck is an enzyme that catalyzes the reversible phosphorylation of creatine cr by adenosine triphosphate atp. Physiologically when muscle contracts atp is converted to adenosine diphosphate adp and ck catalyzes the rephosphorylation of adp to atp using creatine phosphate as the phosphorylation reservoir. Creatine kinase ck is a dimeric enzyme that catalyses the reversible phosphorylation of creatine by atp. This test measures the amount of creatine kinase ck in the blood.
The investigation of musculo skeletal diseases such as muscular dystrophy. This test is used to investigate cardiac or skeletal muscle pathology. 33 211 u l. 7100 15900 umol 24hrs female.
Skeletal muscles are the muscles attached to your skeleton. Creatine kinase ckmb creatinine creatinine clearance cryoglobulin cryoprecipitate. For health information and advice visit nhs uk. Ck is released into blood following damage to muscle tissue resulting in elevated serum plasma ck activity.
Ck rises approximately 6 hours after myocardial infarction mi and may remain elevated for 36 48 hours. The ck enzyme is a dimer composed of subunits derived from. Lab tests online uk is an educational website designed to provide patients and carers with information on laboratory tests used in medical care. The highest creatine kinase on record was over a million and was caused solely by a heavy workout.
It is mostly found in your skeletal muscles and heart with lesser amounts in the brain.